Water masers in the massive protostar IRAS 20126+4104: ejection and deceleration

We report on the first multi-epoch, phase referenced VLBI observations of the water maser emission in a high-mass protostar associated with a disk-jet system. The source under study, IRAS 20126+4104, has been extensively investigated in a large variety of tracers, including water maser VLBA data acquired by us three years before the present observations. The new findings fully confirm the interpretation proposed in our previous study, namely that the maser spots are expanding from a common origin coincident with the protostar. We also demonstrate that the observed 3-D velocities of the maser spots can be fitted with a model assuming that the spots are moving along the surface of a conical jet, with speed increasing for increasing distance from the cone vertex. We also present the results of single-dish monitoring of the water maser spectra in IRAS 20126+4104. These reveal that the peak velocity of some maser lines decreases linearly with time. We speculate that such a deceleration could be due to braking of the shocks from which the maser emission originates, due to mass loading at the shock front or dissipation of the shock energy.Comment: 11 pages, 8 figures. Accepted for publication in A&

Not a galaxy: IRAS 04186+5143, a new young stellar cluster in the outer Galaxy

We report the discovery of a new young stellar cluster in the outer Galaxy located at the position of an IRAS PSC source that has been previously mis-identified as an external galaxy. The cluster is seen in our near-infrared imaging towards IRAS 04186+5143 and in archive Spitzer images confirming the young stellar nature of the sources detected. There is also evidence of sub-clustering seen in the spatial distributions of young stars and of gas and dust. Near- and mid-infrared photometry indicates that the stars exhibit colours compatible with reddening by interstellar and circumstellar dust and are likely to be low- and intermediate-mass YSOs with a large proportion of Class I YSOs. Ammonia and CO lines were detected, with the CO emission well centred near the position of the richest part of the cluster. The velocity of the CO and NH$_3$ lines indicates that the gas is Galactic and located at a distance of about 5.5 kpc, in the outer Galaxy. Herschel data of this region characterise the dust environment of this molecular cloud core where the young cluster is embedded. We derive masses, luminosities and temperatures of the molecular clumps where the young stars reside and discuss their evolutionary stages.Comment: 14 pages, 15 figure

A wide-angle outflow with the simultaneous presence of a high-velocity jet in the high-mass Cepheus A HW2 system

We present five epochs of VLBI water maser observations around the massive protostar Cepheus A HW2 with 0.4 mas (0.3 AU) resolution. The main goal of these observations was to follow the evolution of the remarkable water maser linear/arcuate structures found in earlier VLBI observations. Comparing the data of our new epochs of observation with those observed five years before, we find that at "large" scales of > 1" (700 AU) the main regions of maser emission persist, implying that both the surrounding medium and the exciting sources of the masers have been relatively stable during that time span. However, at smaller scales of < 0.1" (70 AU) we see large changes in the maser structures, particularly in the expanding arcuate structures R4 and R5. R4 traces a nearly elliptical patchy ring of ~ 70 mas size (50 AU) with expanding motions of ~ 5 mas/yr (15 km/s). This structure is probably driven by the wind of a still unidentified YSO located at the centre of the ring (~ 0.18" south of HW2). On the other hand, the R5 expanding bubble structure (driven by the wind of a previously identified YSO located ~ 0.6" south of HW2) is currently dissipating in the circumstellar medium and losing its previous degree of symmetry, indicating a very short-lived event. In addition, our results reveal, at scales of ~ 1" (700 AU), the simultaneous presence of a relatively slow (~ 10-70 km/s) wide-angle outflow (opening angle of ~ 102 deg, traced by the masers, and the fast (~ 500~km/s) highly collimated radio jet associated with HW2 (opening angle of ~ 18 deg, previously observed with the VLA. This simultaneous presence of a wide-angle outflow and a highly collimated jet associated with a massive protostar is similar to what is found in some low-mass YSOs. The implications of these results in the study of the formation of high-mass stars are discussed.Comment: 28 pages, 7 figures. Animations will be included as supporting material online (MNRAS web page

Mycobacterium Tuberculosis Infection and Inflammation: what is Beneficial for the Host and for the Bacterium?

Tuberculosis is still a major health problem in the world. Initial interactions between Mycobacterium tuberculosis and the host mark the pathway of infection and the subsequent host inflammatory response. This inflammatory response is tightly regulated by both the host and the bacterium during different stages of infection. As infection progresses, the initial intense pro-inflammatory response observed is regulated by suppressive mediators balancing inflammation. In this environment, M. tuberculosis battles to survive interfering with the host inflammatory response. In this review we discuss the major effector molecules involved in inflammation in relation to the different stages of M. tuberculosis infection

High-resolution study of a star-forming cluster in the Cep-A HW2 region

Due to its relatively small distance (725 pc), the Cepheus A East star-forming region is an ideal laboratory to study massive star formation processes. Based on its morphology, it has been suggested that the flattened molecular gas distribution around the YSO HW2 may be a 350-AU-radius massive protostellar disk. Goal of our work is to ascertain the nature of this structure. We have employed the Plateau de Bure Interferometer to acquire (sub-)arcsecond-resolution imaging of high-density and shock tracers, such as methyl cyanide (CH3CN) and silicon monoxide (SiO), towards the HW2 position. On the 1-arcsecond (about 725 AU) scale, the flattened distribution of molecular gas around HW2 appears to be due to the projected superposition, on the plane of the sky, of at least three protostellar objects, of which at least one is powering a molecular outflow at a small angle with respect to the line of sight. The presence of a protostellar disk around HW2 is not ruled out, but such structure is likely to be detected on a smaller spatial scale, or using different molecular tracers.Comment: 6 pages, 5 figures, accepted for publication in Astronomy & Astrophysic

Statistical Analysis of Water Masers in Star-Forming Regions: Cepheus A and W75 N

We have done a statistical analysis of Very Long Baseline Array (VLBA) data of water masers in the star-forming regions (SFRs) Cepheus A and W75 N, using correlation functions to study the spatial clustering and Doppler-velocity distribution of these masers. Two-point spatial correlation functions show a characteristic scale size for clusters of water maser spots < or ~1 AU, similar to the values found in other SFRs. This suggests that the scale for water maser excitation tends to be < or ~1 AU. Velocity correlation functions show power-law dependences with indices that can be explained by regular velocity fields, such as expansion and/or rotation. These velocity fields are similar to those indicated by the water maser proper-motion measurements; therefore, the velocity correlation functions appear to reveal the organized motion of water maser spots on scales larger than 1 AU.Comment: 16 pages, 8 figures, and 3 tables. Accepted by The Astrophysical Journa

The Circumstellar Structure and Excitation Effects around the Massive Protostar Cepheus A HW 2

We report SMA 335 GHz continuum observations with angular resolution of ~0.''3, together with VLA ammonia observations with ~1'' resolution toward Cep A HW 2. We find that the flattened disk structure of the dust emission observed by Patel et al. is preserved at the 0.''3 scale, showing an elongated structure of ~$0.''6 size (450 AU) peaking on HW 2. In addition, two ammonia cores are observed, one associated with a hot-core previously reported, and an elongated core with a double peak separated by ~1.''3 and with signs of heating at the inner edges of the gas facing HW 2. The double-peaked ammonia structure, as well as the double-peaked CH3CN structure reported previously (and proposed to be two independent hot-cores), surround both the dust emission as well as the double-peaked SO2 disk structure found by Jimenez-Serra et al. All these results argue against the interpretation of the elongated dust-gas structure as due to a chance-superposition of different cores; instead, they imply that it is physically related to the central massive object within a disk-protostar-jet system.Comment: 12 pages, 3 figures; accepted for publication in the Astrophysical Journa